Cathy Crissy had suffered several stab wounds, police said.
The driver of the pickup truck involved in Sunday's crash, Aaron McGraw, 18, of 156 Jenny Wren Drive, Martinsburg, was treated and released from City Hospital, a hospital spokeswoman said.
Two passengers in the truck, Krystan Roberts and Justin McGraw, were in satisfactory condition at the hospital Monday night, the hospital spokeswoman said.
Police say it appears Crissy's station wagon may have gone left of center when it struck McGraw's pickup truck in a curve at the crest of a hill.
The curve, located just west of the Rocky Glen mobile home park, is a tricky area that has been the scene of other crashes through the years, Chief Deputy Kenny Lemaster said.
Investigators interviewed several people, including Michael Crissy, about the stabbing of Cathy Crissy but have not made any arrests in the stabbing death, West Virginia State Police Sgt. Deke Walker said Monday.
Walker said it is hard to determine whether Michael Crissy's death will have an impact on the investigation into his wife's death.
Walker said Michael Crissy was interviewed at least twice regarding his wife's death, although he was not sure what Crissy was able to provide investigators.
The advantage of having someone you can interview later regarding a crime is that new information can come forward, Walker said.
If someone that police interviewed initially is interviewed again several months later, sometimes that person can recall information that he or she could not remember initially, Walker said.
"I would like to hope his death won't impede the investigation, but it's one of those things you just can't tell," Walker said.
Trooper Robert Elswick, who was shot in the head during a domestic call Oct. 10 near Hedgesville, had been investigating the Cathy Crissy death along with state police detective Dean Olack, Sgt. David Forman said.
Olack will likely handle the Cathy Crissy case, Forman said.
Elswick remains in critical condition at Washington County Hospital.
Michael Crissy was charged with domestic battery following an incident Dec. 29, 2001, at his house in which he allegedly grabbed Cathy Crissy by the throat and threw her against a bed, according to Berkeley County Magistrate Court records.
Crissy told police her husband picked up a knife and came after her, court records said.
Cathy Crissy ran into her son's bedroom and locked the door, court records said.
Michael Crissy kicked in the door and started tearing up the house, court records said.
On Feb. 2 this year, the domestic battery charge against Michael Crissy was "stet docketed," meaning the charge would be dismissed if certain conditions were met, court records said.
The charge would be dismissed against Michael Crissy as long as no additional domestic assault or domestic battery charges were filed against him for a year, court records said.