The industrial park was built at a cost of more than $1 million by the Waynesboro Industrial Development Corporation.
State Sen. Terry Punt, R-Waynesboro, secured a $900,000 state grant to fund construction. The Waynesboro Industrial Development Corporation put up another $100,000.
Punt and State Rep. Patrick Fleagle, R-Waynesboro, spoke briefly at the groundbreaking.
Mike Ross, president of the Franklin County Area Development Corporation, called Monday's groundbreaking "an historic occasion."
Ross said Monday the goal is to have 1,000 jobs in the park. Negotiations are under way with several more potential tenants, officials said.
The new park has 12 lots ranging from five to 12 acres complete with an access road, and water, sewer and gas lines. Access can be gained through two entrances off Pa. 16.
CAM Superline will move into the park after Jan. 1 with its 27 employees and utility trailer assembly line. CAM Treasurer Robert Bentley said employment in the new building could double within the next year and a half.
Bentley, who had a hand in the building's design, said his company will lease the new building with an option to buy later on.
The company is already looking at the next construction phase, which could double its manufacturing space.
"This is phase one," Bentley said.
CAM Superline markets its products through a network of more than 100 dealers in the northeast. Its market includes residential and commercial customers.
The company was established last year by Bentley, Lamar Lehman and Sandy Barrett, and has outgrown its manufacturing space on Bullett Road in Williamson, Barrett said.