Brown's four biggest points came late in the fourth quarter. After Middletown's Trevor Hillier scored to cut Williamsport's lead to 40-36, Brown was fouled going after a rebound. He made both ends of the bonus to push the lead back to six points.
Following a Middletown turnover, Duc Trieu scored and was fouled on a layup. Trieu missed the free throw, but Brown grabbed the rebound and followed with a putback as the Wildcats pulled out to a 46-36 lead with 2:02 left to play.
"That was the big play," Williamsport coach Kevin Murphy said. "Steve (Ritchie) did a great job getting the ball into Duc, and then Andy follows up that foul shot. That sequence was big."
Mike Main, who led the Knights with 15 points, hit two free throws and a jumper from the foul line to get the Knights back to within six with 1:27 to go. But Rusty Tritsch hit the first of two free throws and Artz put back the rebound of the second for a 49-40 lead.
"There's no shame in losing to a good team, and that's what we did tonight," Middletown coach Tim Leber said. "They played great defense and just did a job on us on the boards. They're a solid team that could go a long way this year."
Artz got the Wildcats off to a strong start, scoring 12 points and grabbing 10 rebounds in the first half. His 3-pointer at the start of the second period put Williamsport in front, 20-9. Brown later scored twice off offensive rebounds to give the Wildcats their biggest lead at 30-15.
"Andy (Brown) did the kinds of things tonight that he needs to do to make us a great team," Murphy said. "He did a great job on the offensive boards, got to the foul line and made some big shots. When teams concentrate on Artz, that's what we need him to do."
Artz finished the game with 20 points and 15 rebounds.
Hillier had 10 points for Middletown.